Michelle Theus

Her work focuses on Eph receptor biology following brain injury with an emphasis on neurovascular and neuroimmune health. Eph receptors are developmentally important molecules critical for axon growth & and guidance, which we discovered play a vital role in regulating injury-induced vascular impairment and pro-inflammatory progression. Studies include conditional gene-targeted approaches in murine models of stroke, traumatic brain injury, and post-traumatic epilepsy. Overall, a variety of cellular, molecular, and advanced imaging tools, including single-cell RNAseq, are used to integrate into studies focused on understanding the key mechanistic pathways that play a pivotal role in enhancing the well-being of neurovascular and neuroimmune health.