National Institutes of Health
The Research Instructions for NIH and Other PHS Agencies can be found here:
This document is a comprehensive guide to what is needed in a typical NIH proposal. It also explains the submission process for NIH proposals. At VT, we have access to Cayuse (you can access Cayuse through the OSP website or just search for it on the VT webpage), which is a cloud-based interface with grants.gov that is used in proposal preparation, routing, and submission of externally funded proposals/projects. It simplifies the submission process and will let you know (for the most part) documents/information that are missing, which could make your proposal not be accepted by NIH
The PDF below contains a list of typical documents that MUST be in all NIH proposals (i.e., for R21, R01, etc.) as well as descriptions of what information needs to be in each document.
These two sections that, if funded, are made available on RePORTER to help the public understand the value of NIH-funded research.
Start thinking about your planned experiments by first drafting objectives, known in NIH lingo as Specific Aims. Here are two resources below:
Information for developing an NIH budget, including when you should do a modular budget and when you should have a full budget.
Attachment is required only if the type of application is resubmission or revision or if the FOA specifies that one is needed.
A principal investigator planning to use live vertebrate animals for research, research training, or biological testing. Adhere to requirements, prepare a strong application, and manage your grant at the Research Using Vertebrate Animals link.
Projects or activities that require a team science approach. Instructions are available at the Multiple Principal Investigators page.
NIH expects that key biological and/or chemical resources will be regularly authenticated to ensure their identity and validity for use in the proposed studies
A research study in which one or more human subjects are prospectively assigned to one or more interventions (which may include placebo or other control) to evaluate the effects of those interventions on health-related biomedical or behavioral outcomes.
NIH expects researchers to maximize the appropriate sharing of scientific data, taking into account factors such as legal, ethical, or technical issues that may limit the extent of data sharing and preservation.
Use data tables with Institutional Research Training grant applications and progress reports.
Learn how to address rigor and reproducibility in your grant application and discover what reviewers are looking for as they evaluate the application for scientific merit. More information at Guidance: Rigor and Reproducibility in Grant Applications page.
Advice about what to consider, rules, timing, and tips for the resubmission as well as examples. More information on Revise and Resubmit an Application page.