GSF Empowered Research

Biedler, J.K., Aryan, A., Qi, Y., Wang, A., Martinson, E.O., Hartman, D.A., Yang, F., Sharma, A., Morton, K.S., Potters, M. and Chen, C., 2024. On the origin and evolution of the mosquito male-determining factor Nix. Molecular Biology and Evolution, 41(1), p.msad276.

Brooks, S.G., 2024. Predatory and Mutualistic Interactions between Freshwater Minnows and their Predators (Doctoral dissertation, Virginia Tech).

Farrell, K., Auerbach, A., Musaus, M., Navabpour, S., Liu, C., Lin, Y., Xie, H. and Jarome, T.J., 2024. Phosphorylation of RPT6 controls its ability to bind DNA and regulate gene expression in the hippocampus of male rats during memory formation. Journal of Neuroscience, 44(4).

Keenum, I., Calarco, J., Majeed, H., Hager-Soto, E.E., Bott, C., Garner, E., Harwood, V.J. and Pruden, A., 2024. To what extent do water reuse treatments reduce antibiotic resistance indicators? A comparison of two full-scale systems. Water Research, 254, p.121425.

Kyei, L., Piedl, K., Menegatti, C., Miller, E.M. and Mevers, E., 2024. Discovery of biofilm inhibitors from the microbiota of marine egg masses. Journal of Natural Products, 87(6), pp.1635-1642.

Lawrence, J.A., 2024. Community Ecology of Two Pest Ant Species in Hawaiʻi and a Potential Advancement in Microbial Ant Biocontrol (Master's thesis, University of Hawai'i at Manoa).

Layton, A.R., 2024. Impact of Brewing Industry Byproducts Used as Feed Additives for Aquaculture-Raised Fish: Studies of the Host-Microbe Relationship (Doctoral dissertation, Virginia Tech).

Li, X., Zaia, R., Liu, K., Xu, X., Silva, M.D., Rojas, A., Welbaum, G.E., Zhang, B. and Rideout, S., 2024. Response of the Edamame Germplasm to Early-Season Diseases in the United States. Agronomy, 14(8), p.1660.

Ly, K.E., 2024. Expression and Purification of the C-Terminal Domain of Porcine Epidemic Diarrhea Virus (PEDV) S1 Protein (Doctoral dissertation, Virginia Tech).

Nyblade, Charlotte June. "Gnotobiotic Pig Models for the Study of Enteric Pathogen Replication and Pathogenesis." (2024). (Doctoral dissertation, Virginia Tech).

Okello, I., Nzalawahe, J., Mafie, E. and Eastwood, G., 2024. Seasonal variation in tsetse fly apparent density and Trypanosoma spp. infection rate and occurrence of drug-resistant trypanosomes in Lambwe, Kenya. Parasitology Research, 123(1), p.46.

Piedl, K., Aylward, F.O. and Mevers, E., 2024. The microbiota of moon snail egg collars is shaped by host-specific factors. Microbiology Spectrum, 12(11), pp.e01804-24.

Watkinson, J.I. and Winkel, B.S., 2024. Diversity of unique, nonmycorrhizal endophytic fungi in cultivated Phalaenopsis orchids: A pilot study. Plant‐Environment Interactions, 5(3), p.e10146.

Wei, X., Li, J., Cheng, Z., Wei, S., Yu, G. and Olsen, M.L., 2024. Decoding the Epigenetic Landscape: Insights into 5mC and 5hmC Patterns in Mouse Cortical Cell Types. bioRxiv.

Wu, Yajun, Blake Caldwell, Jing Wang, Yao Zhang, and Liwu Li. "Alleviation of monocyte exhaustion by BCG derivative mycolic acid." Iscience 27, no. 2 (2024).

Caldwell, B.A., Wu, Y., Wang, J. and Li, L., 2023. Altered DNA methylation underlies monocyte dysregulation and innate exhaustion memory in sepsis. bioRxiv, pp.2023-08.

Cereghino, C., Roesch, F., Carrau, L., Hardy, A., Ribeiro-Filho, H.V., Henrion-Lacritick, A., Koh, C., Marano, J.M., Bates, T.A., Rai, P. and Chuong, C., 2023. The E2 glycoprotein holds key residues for Mayaro virus adaptation to the urban Aedes aegypti mosquito. PLoS Pathogens, 19(4), p.e1010491.

DeFoor, N., Paul, S., Li, S., Basso, E.K.G., Stevenson, V., Browning, J.L., Prater, A.K., Brindley, S., Tao, G. and Pickrell, A.M., 2023. Remdesivir increases mtDNA copy number causing mild alterations to oxidative phosphorylation. Scientific Reports, 13(1), p.15339.

Dye, K.J., Salar, S., Allen, U., Smith, W. and Yang, Z., 2023. Myxococcus xanthus PilB interacts with c-di-GMP and modulates motility and biofilm formation. Journal of Bacteriology, 205(9), pp.e00221-23.

Farrell, K., Auerbach, A., Liu, C., Martin, K., Pareno, M., Ray, W.K., Helm, R.F., Biase, F. and Jarome, T.J., 2023. Sex-differences in proteasome-dependent K48-polyubiquitin signaling in the amygdala are developmentally regulated in rats. Biology of sex Differences, 14(1), p.80.

Hines, I.S., Markov Madanick, J., Smith, S.A., Kuhn, D.D. and Stevens, A.M., 2023. Analysis of the core bacterial community associated with consumer-ready Eastern oysters (Crassostrea virginica). Plos one, 18(2), p.e0281747.

Jenrette, J.F., Jenrette, J.L., Truelove, N.K., Moro, S., Dunn, N.I., Chapple, T.K., Gallagher, A.J., Gambardella, C., Schallert, R., Shea, B.D. and Curnick, D.J., 2023. Detecting Mediterranean white sharks with environmental DNA. Oceanography, 36(1), pp.87-89.

Kappel, E.S., V. Cullen, M.J. Costello, L. Galgani, C. Gordó-Vilaseca, A. Govindarajan, S. Kouhi, C. Lavin, L. McCartin, J.D. Müller, B. Pirenne, T. Tanhua, Q. Zhao, and S. Zhao, eds. 2023. Frontiers in Ocean Observing: Emerging Technologies for Understanding and Managing a Changing Ocean. Oceanography 36(Supplement 1), https://doi.org/10.5670/oceanog.2023.s1.

Marano, J.M., Chuong, C. and Weger-Lucarelli, J., 2023. Chapter Two: Rolling Circle Amplification: A high fidelity and efficient alternative to plasmid preparation for the rescue of infectious clones. Development, Characterization, and Use of Molecular Tools to Study Immune-Driven Zika Virus Evolution, p.33.

McFadden, T., Gaito, N., Carucci, I., Fletchall, E., Farrell, K. and Jarome, T.J., 2023. Controlling hypothalamic DNA methylation at the Pomc promoter does not regulate weight gain during the development of obesity. PloS one, 18(4), p.e0284286.

McFadden, Taylor Marie. "Epigenetic and Ubiquitin-Proteasome Mechanisms of Obesity Development." (2023). (Doctoral dissertation, Virginia Tech).

Nita, M., Jones, T., McHenry, D., Bush, E., Oliver, C., Kawaguchi, A., Nita, A. and Katori, M., 2023. A NitroPure Nitrocellulose membrane-based grapevine virus sampling kit: Development and deployment to survey Japanese vineyards and nurseries. Viruses, 15(10), p.2102.

Nix, J.L., Schettini, G.P., Speckhart, S.L., Ealy, A.D. and Biase, F.H., 2023. Ablation of OCT4 function in cattle embryos by double electroporation of CRISPR-Cas for DNA and RNA targeting (CRISPR-DART). PNAS nexus, 2(11), p.pgad343.

Ontoy, J.C., Shrestha, B., Karki, H.S., Barphagha, I., Angira, B., Famoso, A. and Ham, J.H., 2023. Genetic characterization of the partial disease resistance of rice to bacterial panicle blight and sheath blight by combined QTL linkage and QTL-seq analyses. Plants, 12(3), p.559.

Pacholec, C., Carvallo, F.R., Todd, S.M., Ramirez-Barrios, R., Weisman, J. and Zimmerman, K., 2023. What is your diagnosis? Cecal smear in a peafowl. Vet Clin Pathol. 2023;00:1-3. doi:10.1111/vcp.13275

Payne, L.B., Abdelazim, H., Hoque, M., Barnes, A., Mironovova, Z., Willi, C.E., Darden, J., Houk, C., Sedovy, M.W., Johnstone, S.R. and Chappell, J.C., 2023. A soluble platelet-derived growth factor receptor-β originates via Pre-mRNA splicing in the healthy brain and is upregulated during hypoxia and aging. Biomolecules, 13(4), p.711.

Payne, L.B., Abdelazim, H., Hoque, M., Barnes, A., Mironovova, Z., Willi, C.E., Darden, J., Jenkins-Houk, C., Sedovy, M.W., Johnstone, S.R. and Chappell, J.C., 2023. A Soluble Platelet-Derived Growth Factor Receptor-β Originates via Pre-mRNA Splicing in the Healthy Brain and is Differentially Regulated during Hypoxia and Aging. bioRxiv, pp.2023-02.

Thai, K'Ehleyr, Michael W. Taylor, Tatiane Fernandes, Eunice A. Akinade, and Susan L. Campbell. "Topiramate alters the gut microbiome to aid in its anti-seizure effect." Frontiers in Microbiology 14 (2023): 1242856.

Yurchenko, A.A., Naumenko, A.N., Artemov, G.N., Karagodin, D.A., Hodge, J.M., Velichevskaya, A.I., Kokhanenko, A.A., Bondarenko, S.M., Abai, M.R., Kamali, M. and Gordeev, M.I., 2023. Phylogenomics revealed migration routes and adaptive radiation timing of Holarctic malaria mosquito species of the Maculipennis Group. BMC biology, 21(1), p.63.

Banavar, A., Amirkolaei, S.K., Duscher, L., Khairunisa, B.H., Mukhopadhyay, B., Schwarz, M., Urick, S. and Ovissipour, R., 2022. Nutritional evaluation of black soldier fly frass as an ingredient in Florida Pompano (Trachinotus carolinus L.) diets. Animals, 12(18), p.2407.

Chen, C., Compton, A., Nikolouli, K., Wang, A., Aryan, A., Sharma, A., Qi, Y., Dellinger, C., Hempel, M., Potters, M. and Augustinos, A., 2022. Marker-assisted mapping enables forward genetic analysis in Aedes aegypti, an arboviral vector with vast recombination deserts. Genetics, 222(3), p.iyac140.

Cumbie, A.N., Trimble, R.N. and Eastwood, G., 2022. Pathogen spillover to an invasive tick species: first detection of Bourbon virus in Haemaphysalis longicornis in the United States. Pathogens, 11(4), p.454.

Hildreth, S.B., Littleton, E.S., Clark, L.C., Puller, G.C., Kojima, S. and Winkel, B.S., 2022. Mutations that alter Arabidopsis flavonoid metabolism affect the circadian clock. The Plant Journal, 110(4), pp.932-945.

Hurley, K.E., 2022. Maintaining the Genomic Integrity of Staphylococcus aureus in the Presence of Exogenously Induced DNA Damage (Doctoral dissertation, University of Pittsburgh).

Kesselring, J.J.H., 2022. The Influence of Prebiotics, Probiotics, and Exposure to an Opportunistic Pathogen on the Intestinal Microbiome of White Shrimp (Litopenaeus vannamei) (Doctoral dissertation, Virginia Tech).

Knott, B., Kocher, M.A., Paz, H.A., Hamm, S.E., Fink, W., Mason, J., Grange, R.W., Wankhade, U.D. and Good, D.J., 2022. Dietary Conjugated Linoleic Acid Reduces Body Weight and Fat in Snord116m+/p− and Snord116m−/p− Mouse Models of Prader–Willi Syndrome. Nutrients, 14(4), p.860.

Kuchinsky, Sarah. 2022. Determining the Pathogenesis and Enzootic Transmission of Usutu Virus. (Doctoral dissertation, Virginia Tech).

Nyblade, C., Hensley, C., Parreño, V., Zhou, P., Frazier, M., Frazier, A., Ramesh, A., Lei, S., Degiuseppe, J.I., Tan, M. and Yuan, L., 2022. A new gnotobiotic pig model of P [6] human rotavirus infection and disease for preclinical evaluation of rotavirus vaccines. Viruses, 14(12), p.2803.

Pérez‐González, A., Jimenez‐Vicente, E., Salinero‐Lanzarote, A., Harris, D.F., Seefeldt, L.C. and Dean, D.R., 2022. AnfO controls fidelity of nitrogenase FeFe protein maturation by preventing misincorporation of FeV‐cofactor. Molecular microbiology, 117(5), pp.1080-1088.

Roesch, F., Cereghino, C., Carrau, L., Hardy, A., Ribeiro-Filho, H., Lacritick, A.H., Koh, C., Marano, J., Bates, T., Rai, P. and Chuong, C., 2022. The E2 glycoprotein holds key residues for Mayaro virus adaptation to the urban Aedes aegypti mosquito. bioRxiv, pp.2022-04.

Taylor, H., Powers, K.E. and Hallerman, E.M., 2022. Development of a bat guano and acoustic sampling testing protocol to identify species occupying Virginia Department of Transportation bridges (No. FHWA/VTRC 22-R20). Virginia Transportation Research Council (VTRC).

Trusiano, B., Todd, S.M., Barrett, S., Ciepluch, M., Fox, A., McClendon, D., Lahmers, K.K., Oakes, V.J., Carvallo, F., Corrigan, V. and LeCuyer, T.E., 2022. Necrotizing hepatitis caused by Clostridium novyi type B in a dog with no predisposing liver lesions: a case report. BMC Veterinary Research, 18(1), p.366.

Wang, J., Weiss, T., Neidert, M.C., Toussaint, N.C., Naghavian, R., Sellés Moreno, C., Foege, M., Tomas Ojer, P., Medici, G., Jelcic, I. and Schulz, D., 2022. Vaccination with designed neopeptides induces intratumoral, cross-reactive CD4+ T-cell responses in glioblastoma. Clinical Cancer Research, 28(24), pp.5368-5382.

Wilson, C., Dias, N.W., Pancini, S., Mercadante, V. and Biase, F.H., 2022. Delayed processing of blood samples impairs the accuracy of mRNA-based biomarkers. Scientific Reports, 12(1), p.8196.

Bates, T.A., 2021. Usutu Virus: An Emerging Arbovirus Threat (Doctoral dissertation, Virginia Tech).

Bates, T.A., Chuong, C., Hawks, S.A., Rai, P., Duggal, N.K. and Weger-Lucarelli, J., 2021. Development and characterization of infectious clones of two strains of Usutu virus. Virology, 554, pp.28-36.

Chen, C., Compton, A., Nikolouli, K., Wang, A., Aryan, A., Sharma, A., Qi, Y., Delinger, C., Hempel, M., Augustinos, A. and Severson, D.W., 2021. Marker-assisted mapping enables effective forward genetic analysis in the arboviral vector Aedes aegypti, a species with vast recombination deserts. bioRxiv, pp.2021-04.

Compton, A., 2021. Expanding Genetic and Genomic Resources for Sex Separation and Mosquito Control Strategies. (Doctoral Dissertation, Virginia Tech).

Cumbie, A.N., Whitlow, A.M. and Eastwood, G., 2021. First evidence of Powassan virus (Flaviviridae) in Ixodes scapularis in Appalachian Virginia, USA. The American Journal of Tropical Medicine and Hygiene, 106(3), p.905.

Devulapalli, R., Jones, N., Farrell, K., Musaus, M., Kugler, H., McFadden, T., Orsi, S.A., Martin, K., Nelsen, J., Navabpour, S. and O'Donnell, M., 2021. Males and females differ in the regulation and engagement of, but not requirement for, protein degradation in the amygdala during fear memory formation. Neurobiology of learning and memory, 180, p.107404.

Gallucci, A., Patel, D.C., Thai, K.E., Trinh, J., Gude, R., Shukla, D. and Campbell, S.L., 2021. Gut metabolite S‐equol ameliorates hyperexcitability in entorhinal cortex neurons following Theiler murine encephalomyelitis virus‐induced acute seizures. Epilepsia, 62(8), pp.1829-1841.

Gendreau, K.L., Hornsby, A.D., Hague, M.T. and McGlothlin, J.W., 2021. Gene conversion facilitates the adaptive evolution of self-resistance in highly toxic newts. Molecular Biology and Evolution, 38(10), pp.4077-4094.

Harb, C., Pan, J., DeVilbiss, S., Badgley, B., Marr, L.C., Schmale III, D.G. and Foroutan, H., 2021. Increasing freshwater salinity impacts aerosolized bacteria. Environmental Science & Technology, 55(9), pp.5731-5741.

Hildreth, S.B., Littleton, E.S., Clark, L.C., Puller, G.C., Kojima, S. and Winkel, B.S., 2021. Crosstalk between flavonoids and the plant circadian clock. BioRxiv, pp.2021-07.

Lyu, P., Settlage, R.E. and Jiang, H., 2021. Genome-wide identification of enhancers and transcription factors regulating the myogenic differentiation of bovine satellite cells. BMC genomics, 22, pp.1-15.

Saadat, A. and Melville, S.B., 2021. Holin-dependent secretion of the large clostridial toxin TpeL by Clostridium perfringens. Journal of Bacteriology, 203(8), pp.10-1128.

Taetzsch, T., Shapiro, D., Eldosougi, R., Myers, T., Settlage, R.E. and Valdez, G., 2021. The microRNA miR‐133b functions to slow Duchenne muscular dystrophy pathogenesis. The Journal of physiology, 599(1), pp.171-192.

Tsujimoto, H., Anderson, M.A., Eggleston, H., Myles, K.M. and Adelman, Z.N., 2021. Aedes aegypti dyspepsia encodes a novel member of the SLC16 family of transporters and is critical for reproductive fitness. PLoS Neglected Tropical Diseases, 15(4), p.e0009334.

Umans, R.A., Martin, J., Harrigan, M.E., Patel, D.C., Chaunsali, L., Roshandel, A., Iyer, K., Powell, M.D., Oestreich, K. and Sontheimer, H., 2021. Transcriptional regulation of amino acid transport in glioblastoma multiforme. Cancers, 13(24), p.6169.

Wong, A.T., Kawaguchi, A. and Nita, M., 2021. Efficacy of a biological control agent Rhizobium vitis ARK-1 against Virginia R. vitis isolates, and relative relationship among Japanese and Virginia R. vitis isolates. Crop protection, 146, p.105685.

Boni, J.L., Kahanovitch, U., Nwaobi, S.E., Floyd, C.L. and Olsen, M.L., 2020. DNA methylation: A mechanism for sustained alteration of KIR4. 1 expression following central nervous system insult. Glia, 68(7), pp.1495-1512.

Dickerman, A., Bandara, A.B. and Inzana, T.J., 2020. Phylogenomic analysis of Haemophilus parasuis and proposed reclassification to Glaesserella parasuis, gen. nov., comb. nov. International Journal of Systematic and Evolutionary Microbiology, 70(1), pp.180-186.

Eggleston, H. and Adelman, Z.N., 2020. Transcriptomic analyses of Aedes aegypti cultured cells and ex vivo midguts in response to an excess or deficiency of heme: a quest for transcriptionally-regulated heme transporters. BMC genomics, 21, pp.1-20.

Kale, S.D., Mehrkens, B.N., Stegman, M.M., Kastelberg, B., Carnes, H., McNeill, R.J., Rizzo, A., Karyala, S.V., Coutermarsh-Ott, S., Fretz, J.A. and Sun, Y., 2020. “small” intestinal Immunopathology plays a “big” role in lethal cytokine release syndrome, and its modulation by interferon-Γ, IL-17A, and a Janus kinase inhibitor. Frontiers in Immunology, 11, p.1311.

Kuchinsky, S.C., Hawks, S.A., Mossel, E.C., Coutermarsh-Ott, S. and Duggal, N.K., 2020. Differential pathogenesis of Usutu virus isolates in mice. PLoS neglected tropical diseases, 14(10), p.e0008765.

LaConte, L.E., Chavan, V., DeLuca, S., Rubin, K., Malc, J., Berry, S., Gail Summers, C. and Mukherjee, K., 2019. An N‐terminal heterozygous missense CASK mutation is associated with microcephaly and bilateral retinal dystrophy plus optic nerve atrophy. American Journal of Medical Genetics Part A, 179(1), pp.94-103.

Luo, S., Waller, L., Badgley, B., He, Z. and Young, E.B., 2020. Effects of bacterial inoculation and nitrogen loading on bacterial-algal consortium composition and functions in an integrated photobioelectrochemical system. Science of the Total Environment, 716, p.137135.

Macias-Orihuela, Y., Cast, T., Crawford, I., Brandecker, K.J., Thiaville, J.J., Murzin, A.G., de Crécy-Lagard, V., White, R.H. and Allen, K.D., 2020. An unusual route for p-aminobenzoate biosynthesis in Chlamydia trachomatis involves a probable self-sacrificing diiron oxygenase. Journal of Bacteriology, 202(20), pp.10-1128.

Marano, J.M., Chuong, C. and Weger-Lucarelli, J., 2020. Rolling circle amplification: A high fidelity and efficient alternative to plasmid preparation for the rescue of infectious clones. Virology, 551, pp.58-63.